Validation of Geant4 for silicon microdosimetry in heavy ion therapy
نویسندگان
چکیده
منابع مشابه
Performance of silicon microdosimetry detectors in boron neutron capture therapy.
Reverse-biased silicon p-n junction arrays using Silicon-On-Insulator technology have been proposed as microdosimeters. The performance of such detectors in boron neutron capture therapy (BNCT) is discussed. This work provides the first reported measurements using boron-coated silicon diode arrays as microdosimeters in BNCT. Results are in good agreement with measurements with gas proportional ...
متن کاملValidation of New Geant4 Electromagnetic Physics Models for Ion Therapy Applications
1 Nagoya City, Nagoya, Japan 2 Levedev Physics Institute, Moscow, Russia 3 Atomic Institute of the Austrian Universities, Vienna University of Technology, Vienna, Austria 4 CERN, CH-1211 Geveve 23, Swizerland 5 Ecoanalytica, 119899 Moscow, Russia 6 Metz University, LPMC, 57078 Metz, France 7 Geant4 Associates International Ltd, United Kingdom 8 LAPP, 74941 Annecy-le-vieux, France 9 Hyogo Ion Be...
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چکیده ندارد.
15 صفحه اولMicrodosimetry for Targeted Alpha Therapy of Cancer
Targeted alpha therapy (TAT) has the advantage of delivering therapeutic doses to individual cancer cells while reducing the dose to normal tissues. TAT applications relate to hematologic malignancies and now extend to solid tumors. Results from several clinical trials have shown efficacy with limited toxicity. However, the dosimetry for the labeled alpha particle is challenging because of the ...
متن کاملTissue equivalence correction for silicon microdosimetry detectors in boron neutron capture therapy.
Reverse-biased silicon p-n junction arrays have been proposed as microdosimetry detectors. The tissue equivalence of such detectors in boron neutron capture therapy (BNCT) is discussed. A comparison of the range-energy relationships of H, He, C, and Li ions in tissue (ICRU-muscle) and silicon is given. A simple geometrical scaling (approximately 0.63) of linear dimensions is required to convert...
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ژورنال
عنوان ژورنال: Physics in Medicine & Biology
سال: 2020
ISSN: 1361-6560
DOI: 10.1088/1361-6560/ab586a